Cold and warm water fishing are available during the appropriate season in several creeks that wind through Moshannon State Forest, such as:
- Mix Run
- Medix Run
- Gifford Run
- Mosquito Creek
- Laurel Run
- Anderson Creek
Fishing opportunities in the southern part of the district include Black Moshannon Creek, Six Mile Run, and Meyers Run.
Two shallow water impoundments offer warm water fishing and an opportunity to view migrating waterfowl. In addition to many of the local streams, the Shaggers Inn Shallow Water Impoundment is annually stocked with trout in early April.
The nearby West Branch Susquehanna River offers some excellent canoeing opportunities as well.